Biomedical Research Facilities (C06 Clinical Trial Not Allowed) | PAR 22 088

Opportunity Information: Apply for PAR 22 088

The National Institutes of Health (NIH) grant opportunity "Biomedical Research Facilities (C06 Clinical Trial Not Allowed)" (Funding Opportunity Number PAR-22-088; CFDA 93.352) supports capital projects that strengthen an institution's ability to conduct biomedical research by improving the physical research environment. The focus is on facilities rather than research studies, meaning the funding is intended to modernize existing space or construct new space that will serve biomedical research programs over the long term. Clinical trials are not allowed under this announcement, reflecting that the award is meant for infrastructure development rather than human-subjects intervention studies.

At its core, this program is designed to expand and upgrade shared biomedical research infrastructure. NIH is looking for projects that produce durable, institution-wide benefits, not one-off renovations for a single lab or a narrowly defined project team. The targeted scope includes construction or major modernization of core facilities and other shared resources that serve a broad research community on a shared-use basis. In practical terms, that generally points to spaces like centralized cores, shared instrumentation areas, and other backbone facilities that multiple departments, centers, or investigators rely on. The expectation is that the investment will translate into stronger institutional research capacity and a measurable improvement in the environment where biomedical research is carried out.

NIH explicitly encourages applications from a wide range of institutions across all U.S. geographic regions, including both highly research-intensive organizations and "Institutions of Emerging Excellence" that are still building their biomedical research footprint. The announcement also highlights the importance of all higher-education institutions to the nation's research capacity, signaling an intent to support a broad spectrum of applicants rather than concentrating support only among the largest research enterprises. The overall goal is to help institutions develop modern, competitive research facilities that can support current needs and position them well for future growth in biomedical research.

Eligibility is broad and spans many organizational types, including public and private nonprofit institutions of higher education and nonprofit research organizations. The source data also lists additional eligible applicant categories such as state, county, and local governments; special district governments; independent school districts; federally recognized tribal governments and certain tribal organizations; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (outside higher education); private institutions of higher education; and even for-profit organizations and small businesses (as reflected in the eligibility table). Beyond that, the FOA explicitly calls out and welcomes applications from mission- and community-focused institution types and organizations, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions.

At the same time, the opportunity draws clear boundaries around foreign involvement. Non-domestic (non-U.S.) entities (foreign organizations and foreign institutions) are not eligible to apply. In addition, non-domestic components of U.S. organizations are not eligible, and foreign components (as defined by the NIH Grants Policy Statement) are not allowed. In short, the applicant organization and the supported facility work must be firmly based within the United States and its eligible jurisdictions, without foreign components embedded in the project.

Administratively, this is a discretionary grant program under NIH, categorized under the health funding activity area. The opportunity was created on January 4, 2022, and the original closing date listed is March 25, 2022. The listing provided does not specify an award ceiling or the expected number of awards, so applicants typically would need to consult the full FOA text and any related NIH guidance for budget limits, cost principles, allowable and unallowable costs, cost-sharing expectations (if any), and the review criteria used to evaluate facility proposals.

Overall, the program is best understood as NIH support for bricks-and-mortar research capability: modern, shared biomedical research spaces that elevate an institution's long-term infrastructure and, in turn, its competitiveness and productivity in biomedical research. The strongest proposals under a program like this usually emphasize institution-wide impact, shared access and governance, sustainability of the facility over time, and how the upgraded or new facility directly enables a stronger, broader biomedical research enterprise rather than benefiting a single investigator or narrowly defined project.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Biomedical Research Facilities (C06 Clinical Trial Not Allowed)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.352.
• This funding opportunity was created on 2022-01-04.
• Applicants must submit their applications by 2022-03-25. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PAR 22 088

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