Opportunity Information: Apply for SP 23 004
The Strategic Prevention Framework - Partnerships for Success for Communities, Local Governments, Universities, Colleges, and Tribes/Tribal Organizations is a discretionary federal grant opportunity from the U.S. Department of Health and Human Services, administered by the Substance Abuse and Mental Health Services Administration (SAMHSA). It is designed to help communities prevent substance misuse before it starts, slow or stop escalation when early risk is present, and reduce related harms by investing in locally driven prevention services and mental health promotion activities. The core focus is on building and expanding the capacity of community prevention providers so they can plan, implement, and sustain evidence-based prevention programs that fit local needs and conditions.
This opportunity is centered on community-based prevention, meaning applicants are expected to work close to where problems show up and where protective factors can be strengthened: neighborhoods, schools, campuses, local service systems, and tribal communities. The grant supports efforts that promote mental health and prevent substance misuse through structured prevention strategies rather than treatment services. In practical terms, this typically means strengthening prevention infrastructure (such as community coalitions and prevention providers), improving local planning and coordination, selecting interventions with evidence behind them, and delivering those interventions with enough quality and consistency to produce measurable outcomes.
The funding opportunity number is SP 23 004, and it is listed under CFDA 93.243 in the Health activity category. The award ceiling is $375,000 per award, and SAMHSA anticipates making about 44 awards under this announcement. Funding is provided through a grant instrument, and the program is intended for a range of applicants identified broadly as eligible entities, including communities, local governments, universities and colleges, and tribes or tribal organizations (with the official eligibility details referenced in the notice under an "Additional Information on Eligibility" section).
A key feature of this notice of funding opportunity is that it stays open across three federal fiscal years, giving organizations multiple chances to apply. Application deadlines are tied to each fiscal year: June 5, 2023 for FY 2023; June 5, 2024 for FY 2024; and June 5, 2025 for FY 2025. Applications submitted by the relevant due date are reviewed within that fiscal year, with funding decisions expected by the end of the fiscal year. If an applicant does not receive an award in one year, they are allowed to apply again in the next fiscal year while the notice remains open. The opportunity was created on April 3, 2023, and the original closing date listed is June 5, 2025, aligning with the final year deadline.
Overall, this program is best understood as prevention capacity-building plus delivery of proven prevention approaches. It aims to strengthen local prevention systems so that communities can more effectively reduce risk factors, increase protective factors, and implement strategies that have demonstrated impact on substance misuse prevention and mental health promotion outcomes.Apply for SP 23 004
- The Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis in the health sector is offering a public funding opportunity titled "Strategic Prevention Framework – Partnerships for Success for Communities, Local Governments, Universities, Colleges, and Tribes/Tribal Organizations" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.243.
- This funding opportunity was created on Apr 03, 2023.
- Applicants must submit their applications by Jun 05, 2025. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $375,000.00 in funding.
- The number of recipients for this funding is limited to 44 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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| Funding Opportunity |
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| Assuring Comprehensive Perinatal, Maternal and Infant Health and the Elimination of Perinatal HIV in the United States Apply for CDC RFA PS23 0013 Funding Number: CDC RFA PS23 0013 Agency: Department of Health and Human Services, Centers for Disease Control - NCHHSTP Category: Health Funding Amount: Case Dependent |
| Strengthening Public Health Systems and Services in Indian Country Apply for CDC RFA TO 23 0001 Funding Number: CDC RFA TO 23 0001 Agency: Department of Health and Human Services, CENTERS FOR DISEASE CONTROL CSTLTS Category: Health Funding Amount: Case Dependent |
| Global Emergency Response and Recovery Partner Engagement: Expanding Efforts and Strategies to Improve Rapid Response to Public Health Emergencies Globally Apply for CDC RFA GH 23 0042 Funding Number: CDC RFA GH 23 0042 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Community Health Equity through Systems Strengthening (CHESS) Apply for CAM RFI 00001 Funding Number: CAM RFI 00001 Agency: Agency for International Development, Ghana USAID-Accra Category: Health Funding Amount: $2,000,000 |
| Teen Pregnancy Prevention Tier 2 Adolescent Sexual Health Innovation Hubs Apply for AH TP2 23 002 Funding Number: AH TP2 23 002 Agency: Department of Health and Human Services, Office of the Assistant Secretary for Health Category: Health Funding Amount: $2,000,000 |
| Increasing Public Awareness and Provider Education About Primary Immunodeficiency Disease Apply for CDC RFA CD 23 0057 Funding Number: CDC RFA CD 23 0057 Agency: Department of Health and Human Services, Centers for Disease Control - OD Category: Health Funding Amount: $3,000,000 |
| Radiation protection of workers and the public by state and local radiation control programs Apply for CDC RFA EH 23 0004 Funding Number: CDC RFA EH 23 0004 Agency: Department of Health and Human Services, Centers for Disease Control - NCEH Category: Health Funding Amount: $110,000 |
| Lowlands Health Activity Apply for 72066323RFA00007 Funding Number: 72066323RFA00007 Agency: Agency for International Development, Ethiopia USAID-Addis Ababa Category: Health Funding Amount: $35,000,000 |
| Behavioral Health Partnership for Early Diversion of Adults and Youth Apply for SM 23 012 Funding Number: SM 23 012 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $330,000 |
| Pediatric Mental Health Care Access Program Apply for HRSA 23 081 Funding Number: HRSA 23 081 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| A Status Neutral Approach to Improve HIV Prevention and Health Outcomes for Racial and Ethnic Minorities – Evaluation and Technical Assistance Provider (ETAP) Apply for HRSA 23 127 Funding Number: HRSA 23 127 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $2,250,000 |
| A Status Neutral Approach to Improve HIV Prevention and Health Outcomes for Racial and Ethnic Minorities – Implementation Sites Apply for HRSA 23 126 Funding Number: HRSA 23 126 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $500,000 |
| Preventive Health and Health Services Block Grant– 2023 CDC-RFA-TO23-2304 Apply for CDC RFA TO23 2304 Funding Number: CDC RFA TO23 2304 Agency: Department of Health and Human Services, CENTERS FOR DISEASE CONTROL CSTLTS Category: Health Funding Amount: Case Dependent |
| Essentials for Childhood (EfC): Preventing Adverse Childhood Experiences through Data to Action Apply for CDC RFA CE 23 0005 Funding Number: CDC RFA CE 23 0005 Agency: Department of Health and Human Services, Centers for Disease Control - NCIPC Category: Health Funding Amount: $485,000 |
| State Maternal Health Innovation Program Apply for HRSA 23 108 Funding Number: HRSA 23 108 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $2,000,000 |
| Maternal Health Research Collaborative for Minority-Serving Institutions (MH-RC-MSI) Coordinating Center (CC) Apply for HRSA 23 113 Funding Number: HRSA 23 113 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $2,350,000 |
| Maternal Health Research Collaborative for Minority-Serving Institutions (MH-RC-MSI) Research Centers (RCs) Apply for HRSA 23 112 Funding Number: HRSA 23 112 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $461,000 |
| Enhancing STI and Sexual Health Clinic Infrastructure (ESSHCI) Apply for CDC RFA PS 23 0011 Funding Number: CDC RFA PS 23 0011 Agency: Department of Health and Human Services, Centers for Disease Control - NCHHSTP Category: Health Funding Amount: Case Dependent |
| Tribal Self-Governance Planning Cooperative Agreement Program Apply for HHS 2023 IHS TSGP 0001 Funding Number: HHS 2023 IHS TSGP 0001 Agency: Department of Health and Human Services, Indian Health Service Category: Health Funding Amount: $180,000 |
| CDC-Mexico Cooperative Agreement for Surveillance, Epidemiology, and Laboratory Capacity Apply for CDC RFA CK 23 0054 Funding Number: CDC RFA CK 23 0054 Agency: Department of Health and Human Services, Centers for Disease Control - NCEZID Category: Health Funding Amount: Case Dependent |
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