The Health of Sexual and Gender Minority (SGM) Populations (R21 Clinical Trial Optional) | PA 18 040

Opportunity Information: Apply for PA 18 040

The Health of Sexual and Gender Minority (SGM) Populations (R21 Clinical Trial Optional) funding opportunity (PA 18-040) is a National Institutes of Health (NIH) research grant solicitation designed to strengthen the evidence base on the health of sexual and gender minority populations. NIH frames the goal in practical terms: build scientific understanding of health status, risks, and needs in diverse groups so that health interventions and services can be made more effective. A major emphasis is placed on populations that have been historically understudied and that may face distinctive or elevated risk profiles, with this announcement specifically centering SGM communities, including lesbian, gay, bisexual, transgender, and intersex people.

The FOA invites a wide range of research approaches as long as they are relevant to the missions of participating NIH Institutes and Centers. That includes basic research as well as social, behavioral, clinical, and health services research. In other words, projects can focus on foundational mechanisms, individual and community behavior, clinical outcomes, and the way care is delivered and accessed. The "clinical trial optional" label signals that applicants may propose studies that include a clinical trial component, but they are not required to do so; non-trial projects are also responsive if they advance knowledge about SGM health.

This opportunity uses the NIH R21 mechanism, which is typically intended for exploratory and developmental projects that can generate new insights, pilot data, novel methods, or early-stage findings that can later be scaled or pursued through larger awards. The funding instrument type is a grant, and the opportunity is categorized as discretionary. The listed award ceiling is $200,000, which indicates an upper bound on the amount that can be requested under the parameters reflected in the provided source information. The announcement is tied to multiple CFDA numbers (including 93.121, 93.173, 93.242, 93.279, 93.307, 93.393, 93.394, 93.395, 93.396, 93.399, 93.855, 93.856, 93.865), reflecting that multiple NIH components may support awards aligned with their specific program priorities.

Eligibility is intentionally broad to encourage participation from many sectors that can contribute to SGM health research. Eligible applicants include state, county, city or township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations other than federally recognized governments; public housing authorities and Indian housing authorities; nonprofits with and without 501(c)(3) status (other than institutions of higher education); for-profit organizations (other than small businesses); small businesses; and other applicants as permitted by NIH policy. The FOA also explicitly calls out additional eligible applicant types, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and non-domestic (non-U.S.) entities (foreign organizations). This broad eligibility is consistent with NIH interest in reaching communities and institutions that are positioned to study, engage, and serve SGM populations, including those that may be underrepresented in research.

Administratively, the sponsoring agency is NIH, and the opportunity’s record shows a creation date of 2017-11-06 with an original closing date listed as 2018-09-07. The announcement is presented as supporting research to improve understanding and, ultimately, improve interventions and services for SGM individuals through rigorous scientific study across disciplines.

• The National Institutes of Health in the education, health, income security and social services sector is offering a public funding opportunity titled "The Health of Sexual and Gender Minority (SGM) Populations (R21 Clinical Trial Optional)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121, 93.173, 93.242, 93.279, 93.307, 93.393, 93.394, 93.395, 93.396, 93.399, 93.855, 93.856, 93.865.
• This funding opportunity was created on 2017-11-06.
• Applicants must submit their applications by 2018-09-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $200,000.00 in funding.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

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